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Trent University MS PhD Position Coevolutionary Mechanisms in Pathogen Vector Complexes
January 6, 2008
Coevolutionary Mechanisms in Pathogen/Vector Complexes
I will have positions available for MSc and/or PhD candidates to
investigate coevolutionary mechanisms using the raccoon rabies virus
and its vectors as a model system.
The dynamic interaction between species and their pathogens plays a
pivotal role in their adaptation, evolution, and persistence. Conventional
belief suggests that rabies is a lethal disease with no potential for
evolution within its hosts. Disease challenge and vaccination experiments,
however, indicate that variability exists in the immune response
of raccoons to rabies. This project will involve an investigation of
selective responses of raccoons to rabies via genes that are intimately
associated with the initiation of an immune response and studied in
relation to the absence, presence and duration of rabies exposure. These
data will be used to empirically test theories of balancing selection,
frequency-based selection, the geographic mosaic theory of co-evolution,
and contribute to our understanding of mechanisms involved in disease
spread and maintenance.
Research will take place within the new DNA Building at Trent University
that houses the Natural Resources DNA Profiling and Forensics Centre and
the Wildlife Research and Development Section of the Ontario Ministry
of Natural Resources. This venue provides an exciting collaborative
research environment with field and lab-based researchers and unsurpassed
infrastructure for wildlife genetic and wildlife disease research. Refer
to the websites below for further information.
Candidates are expected to commence their studies between May - September
2008. Interested individuals should provide a recent CV with referee
contact information, copies of any publications, approximate GPA,
and a brief description of their interest in the position. A review
of applications will begin on February 1, 2008 and continue until the
positions are filled.
Contact: Dr. C. J. Kyle
Research Chair in Wildlife Genetics and Forensics
Natural Resources DNA Profiling and Forensics Centre
Trent University, 2140 East Bank Drive
Peterborough, ON, K9J 7B8
chris.kyle@nrdpfc.ca
Tags: Coevolutionary Mechanisms, MS PhD Position, Pathogen Vector Complexes
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